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Will Wave Life Sciences maintain cash and equivalents above $400M at Q3 2026 quarter-end?

Resolves November 15, 2026(131d)
IG: 0.64

Current Prediction

59%
Likely Yes
Model Agreement96%
Predictions9 runs
Last UpdatedApril 8, 2026

Why This Question Matters

Cash runway is the binding constraint identified by the Stress Scanner. Quarterly cash balance below $400M without announced financing would signal compressed runway. This market tests whether the burn rate remains manageable or accelerates beyond guidance.

FUNDING_FRAGILITYCAPITAL_DEPLOYMENT

Prediction Distribution

0%25%50%75%100%
opus
sonnet
haiku
Range: 51%66%Aggregate: 59%
Individual Predictions(9 runs)
opusRun 1
60%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Starting at $602M with Q3 2028 guided runway provides partial support, but r&d at $52.8m and rising creates counterweight. Probability: 0.6.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising
opusRun 2
51%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Starting at $602M with Q3 2028 guided runway provides partial support, but r&d at $52.8m and rising creates counterweight. Probability: 0.51.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising
opusRun 3
56%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Starting at $602M with Q3 2028 guided runway provides partial support, but r&d at $52.8m and rising creates counterweight. Probability: 0.56.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising
sonnetRun 1
56%

Base rate evidence: r&d at $52.8m and rising. Partial offset from starting at $602m with q3 2028 guided runway. Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Probability: 0.56.

R&D at $52.8M and risingCentral estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runway
sonnetRun 2
61%

Base rate evidence: r&d at $52.8m and rising. Partial offset from starting at $602m with q3 2028 guided runway. Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Probability: 0.61.

R&D at $52.8M and risingCentral estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runway
sonnetRun 3
66%

Base rate evidence: r&d at $52.8m and rising. Partial offset from starting at $602m with q3 2028 guided runway. Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Probability: 0.66.

R&D at $52.8M and risingCentral estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runway
haikuRun 1
58%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Balance of evidence suggests 0.58 probability. Primary support: starting at $602m with q3 2028 guided runway. Main counterargument: r&d at $52.8m and rising.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising
haikuRun 2
60%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Balance of evidence suggests 0.6 probability. Primary support: starting at $602m with q3 2028 guided runway. Main counterargument: r&d at $52.8m and rising.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising
haikuRun 3
59%

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate acceleration. Balance of evidence suggests 0.59 probability. Primary support: starting at $602m with q3 2028 guided runway. Main counterargument: r&d at $52.8m and rising.

Central estimate ~$430-450M at Q3 2026, but sensitive to burn rate accelerationStarting at $602M with Q3 2028 guided runwayR&D at $52.8M and rising

Resolution Criteria

Resolves YES if Wave reports cash, cash equivalents, and short-term investments above $400M at Q3 2026 quarter-end. Resolves NO if below $400M.

Resolution Source

Wave Life Sciences Q3 2026 10-Q filing

Source Trigger

Cash balance at $602M (Q4 2025); below $400M without financing would signal compressed runway. R&D burn at $52.8M/quarter and accelerating

stress-scannerFUNDING_FRAGILITYHIGH
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